Burré Laboratory

News

18. July 2022: Manu Sharma and Jacqueline wrap up their editorial special issue with the article “Cellular and small animal models of neurodegenerative diseases” in JoVE.

8. July 2022: Jacqueline gives a plenary lecture at the ISCCB in Hamburg, Germany on the lab’s work on Munc18-1.

5. July 2022: Welcome, Katherine! Katherine Tsang joins the lab as rotation student.

27. June 2022: Congrats, Virginia, Jack and Lauren. The review article “Functional and pathological effects of α-synuclein on synaptic SNARE complexes” in Journal of Molecular Biology has been accepted for publication as part of the special issue “Protein Membrane Interactions at the Synapse”.

16. June 2022: Virginia and Jacqueline, together with our clinical collaborators Dr. Andrea Lee, Dr. Alexander Shtilbans and Dr. Carl Crawford, receive a CTSC Pilot Award to study alpha-synuclein in the human gut.

15. June 2022: Lauren was awarded an NRSA F31 fellowships from NINDS to study the synaptic role of beta-synuclein. Congratulations!

06. June 2022: Welcome, Saad! Saad starts as research technician in the lab.

26. May 2022: Virginia presents a poster at the 4th Pan American Parkinson’s Disease and Movement Disorders Congress.

18. May 2022: Ari and Virginia present at the 8th Annual Neurology Resident Research Symposium.

17. May 2022: Aniv receives a postdoctoral fellowship from the American Epilepsy Society for her studies on STXBP1. Congratulations!

15. April 2022: Manu Sharma and Jacqueline receive an MPI RF1 on the impact of beta- and gamma-synucleins on alpha-synuclein’s synaptic function.

12. April 2022: Katie’s and Lauren’s study on the effects of beta- and gamma-synuclein on alpha-synuclein function is published in Cell Reports (https://pubmed.ncbi.nlm.nih.gov/35417693/) – congrats!!!

12. April 2022: Lauren, Virginia and Jacqueline travel to Leuven, Belgium, to the Synuclein 2022 conference. Lauren presents a poster on her just published study “Synaptic vesicle binding of α-synuclein is modulated by β- and γ-synucleins” (https://pubmed.ncbi.nlm.nih.gov/35417693/). Virginia gives a talk on “Early biochemical changes in alpha-synuclein in the central and enteric nervous system in Parkinson’s disease”. Jacqueline gives a plenary talk on function and dysfunction of alpha-synuclein – membranes matter!”.

6. April 2022: Jacqueline present to the WCM Department of Neurology, Division of Neurodegenerative Diseases on the lab’s translational alpha-synuclein work.

5. April 2022: Jacqueline presents at the WCM Neurodegeneration PI meeting about Synaptopathies in neurodevelopment and neurodegeneration.

2. April 2022: Virginia presents a poster at the AAN meeting in Seattle.

30. March 2022: Aniv and Jacqueline host the Children’s Health Council for an update on the lab’s translational work on STXBP1 encephalopathies and a lab tour. See also: https://give.weill.cornell.edu/childrens-health-council

24. February 2022: Jacqueline gives a guest lecture to students at Vanderbilt University about the lab’s translational work on Munc18-1/STXBP1.

23. February 2022: Jacqueline presents at the Motor Neuron Center at Columbia University on the lab’s studies on Munc18-1/STXBP1.

1. February 2022: Jacqueline receives funding from the MDBR Grant Program, The Orphan Disease Center, Penn Medicine for our translational studies of rescuing compounds on Munc18-1 stability in vivo in mouse models.

31. January 2022: Jack receives a Research Supplement to Promote Diversity in Health-Related Research from NINDS for this studies on alpha-synuclein. Congratulations, Jack!

17. Dec 2021: Virginia receives a travel award to attend the 4th Pan American Parkinson’s Disease and Movement Disorders Congress. Congratulations, Virginia!

16. Dec 2021: Virginia receives a travel award (“Futures in Neurology Research scholarship”) to attend the 2022 Annual Meeting of the Academy of Neurology. Congratulations!

3. Dec 2021: Virginia receives a Research Scholarship from the American Academy of Neurology. Congrats!!!

18-19 Nov 2021: Jacqueline co-organizes the STXBP1 Roundtable 2021, and chairs the session for “Mechanisms of Disease”.

9. Nov 2021: Jacqueline presents at the 9th Appel Alzheimer’s Disease Research Institute Symposium.

26-27 Oct 2021: Intercampus Symposium on Aging and Neurodegeneration. Virginia presents on “Biochemical changes in alpha-synuclein in the central and enteric nervous system in Parkinson’s disease”, and Jacqueline presents on “Synucleins in aging and neurodegeneration”

23. Sept 2021: Virginia presents her work on alpha-synuclein mediated pathology in the CNS and ENS in Parkinson’s disease at the 2021 Postdoc research day.

19. Sept 2021: Jacqueline presents the lab’s work on small molecule therapies for STXBP1 encephalopathies at the 2021 STXBP1 Summit.

05. July 2021: Welcome, Ari! Ari starts as BMRI Research Fellow in the Burré lab.

21. June 2021: Welcome, Jack! Jack starts today as Research Technician I in the Burré lab.

16. June 2021: Debby present her work on Munc18-1/STXBP1-targeted pharmacological chaperones today at the Research in Progress Seminar Series of the Molecular Biophysics Training Program.

03. June 2021: Congratulations, Dr. Debby Abramov! Debby has defended her thesis today.

12. May 2021: Jacqueline present at the Presynaptic Dysfunction Symposium, hosted by the Journal of Neurochemistry.

06. May 2021: Virginia receives the McGraw Fellowship in Neurology Research. The McGraw Fellow is chosen based on high-quality, compassionate, and scholarly care for patients as well as the initiative to develop a research interest that has potential to benefit patients with neurological disease.  Congrats, Virginia!

07. Apr 2021: Jacqueline receives the third R01 for her work with Dr. Jiajie Diao at the University of Cincinnati on understanding the role of VAMP2 in alpha-synuclein function and pathology.

05. Apr 2021: Congratulations, Virginia! Virginia got promoted to Chief Resident.

01. Apr 2021: Congratulations, Yoonmi! Yoonmi gets promoted to Research Associate for her outstanding and meticulous scientific work.

10. Mar 2021: Virginia presents her work “alpha-Synuclein in the central and enteric nervous systems in Parkinson’s disease” at the Appel Institute Forum on Neurodegeneration

23. Dec 2020: Virginia receives the Leon Levy Fellowship in Neuroscience. Congratulations!!!

17. Dec 2020: Debby’s paper is out. Read at https://www.embopress.org/doi/full/10.15252/emmm.202012354

04. Dec 2020: Katie presents her work “Function and Dysfunction of alpha-synucleins: Membranes Matter!” during the BMRI Work in Progress Seminar series

11. Nov 2020: Debby’s paper is accepted in EMBO Molecular Medicine. Congratulations!

04. Nov 2020: Jacqueline present the lab’s work on alpha-synuclein in a meeting of the Parkinson’s Disease Consortium at the Michael J. Fox Foundation.

06. Oct 2020: Congratulations, Aniv! Aniv receives the Osias and Taube Schlomiuk award for excellent PhD work.

05. Oct 2020: Jacqueline presents the lab’s work on Munc18-1 at the Biology Department Weekly Seminar at Boston University.

22. Sept 2020: Debby, Noah, Zach and Jacqueline – Team Weill Cornell – present the recent advances on research and pilot clinical trial for children with mutations in STXBP1 at the STXBP1 Awareness Month Webinar Series.

22. Sept 2020: Jacqueline presents the lab’s synuclein work at the Oxford Parkinson’s Disease Centre.

13. Sept 2020: Aniv receives the Hebrew University Scholarship for Female Postdocs. Congratulations!!!

01. Sept 2020: It’s STXBP1 Awareness Month! https://www.stxbp1disorders.org/events/september-is-stxbp1-disorders-awareness-month

12. Aug 2020: Virginia presents her work at the Sixth Annual Neurology Resident Research Symposium.

03. Aug 2020: Debby receives an NRSA F30 fellowship. Congrats!!!!!

27. Jul 2020: Lab meetings are still fun!

20. Jul 2020: Our pilot clinical trial on the biochemical characterization of Parkinson’s disease-related proteins in the enteric nervous system is launching! https://jcto.weill.cornell.edu/open_clinical_trials/biochemical-characterization-of-parkinsons-disease-related-proteins-in-the-enteric-nervous-system

01. Jul 2020: Welcome, Aniv! Aniv Brukner starts her postdoctoral fellowship today.

30. Jun 2020: Debby’s and Noah’s review article about STXBP1 encephalopathies is accepted in The Journal of Neurochemistry – hooray!

01. Jun 2020: Jacqueline receives NIH funding for our studies on alpha-synuclein.

15. Apr 2020: Jacqueline receives the BMRI 2019 Mentor of the Year Award. Thank you all – what a wonderful surprise!

14. Apr 2020: Congratulations, Lauren! Lauren has passed her ACE. Only a virtual cake because of COVID-19 shutdown 🙁

28. Feb 2020: Debby presents her work at the BMRI Work in Progress Seminar Series.

25. Feb 2020: Jacqueline presents to the Molecular & Cellular Biology Program at the University of Massachussettes Amherst.

12. Feb 2020: Debby presents her work at the Appel Institute Forum on Neurodegeneration.

10. Feb 2020: Our work with the Sharma lab is published in Nature Structural & Molecular Biology. Congratulations, Nima! https://pubmed.ncbi.nlm.nih.gov/32042150/

21. Jun 2019: Noah, Debby and Jacqueline present at the first STXBP1 Investigators & Family Meeting in Philadelphia.

13. Sept 2019: Congratulations, Dr. Pineda! André defended his thesis today.

04. Aug 2019: Jacqueline is invited to present at the International Society for Neurochemistry Meeting in Montreal.

13. Jun 2019: Noah receives the Markey Graduate School of Medical Science Fellowship. Congratulations!

05. Apr 2019: Jacqueline presents her work to the Department of Neuroscience at Baylor College of Medicine.

20. Mar 2019: Jacqueline presents our work on Munc18-1 to the Biology Department at St. Johns University.

15. Jan 2019: Jacqueline receives funding from the Michael J. Fox Foundation.

13. Nov 2018: Welcome, Lauren! Lauren Komer starts her rotation in the Burré lab.

29. Oct 2018: Welcome, Nicole! Nicole Mollé starts her rotation in the lab

19. Oct 2018: Congrats, Debby, for passing your ACE!

02. Oct 2018: Jacqueline presents to the Graduate Interdisciplinary Program at the University of Arizona on our Munc18-1 studies.

28. Sept 2018: Noah’s & André’s paper is published in Nature Communications – congrats! https://pubmed.ncbi.nlm.nih.gov/30266908/

06. Aug 2018: Welcome, Yoonmi! Yoonmi Na starts as research specialist. We are all very excited!

19. Jul 2018: Jacqueline and Virginia present to the Weill Cornell Internal Medicine Associates to recruit patients for their human studies.

02. Jul 2018: Welcome, Victoria! Victoria von Saucken joins the Burré lab as rotation student.

30. May 2018: Katie receives the Markey Graduate School of Medical Science Fellowship. Congratulations!

20. Apr 2018: Noah presents his work at the Feil Family Brain and Mind Research Institute Work in Progress Seminar Series. Awesome job, Noah!

18. Jan 2018: Noah presents his work at PINS.

19. Jul 2017: Congrats, Katie, for passing your ACE!

03. Jul 2017: Welcome, Debby! Debby Abramov starts her rotation today.

15. Feb 2017: Congrats, Noah, for passing your ACE!

26. Jan 2016: Our invited commentary is published in PNAS. https://pubmed.ncbi.nlm.nih.gov/28126719/

20. Dec 2016: Jacqueline receives the Sanofi Innovation Award-

16. Nov 2016: Noah, André and Katie present their work at the 2016 SfN in San Diego.

05. Oct 2016: Jacqueline presents at the Appel Alzheimer’s Disease Research Institute Symposium on “Function and Dysfunction of alpha-synuclein – Membranes matter”.

From left to right: Dr. Iadecola, Dr. Holtzman, Dr. Haeberlein, Dr. Choi, Mr. Appel, Dr. Petsko, and Dr. Burré.

08. Jun 2016: Congrats, André, for passing your ACE!

23. May 2016: Jacqueline presents to the Scientific Advisory Board of the American Parkinson Disease Association.

06. May 2016: Jacqueline presents at the AbbVie Pharma Day.

21. Apr 2016: Noah presents his work at the du Vigneaud Research Symposium.

19. Apr 2016: Jacqueline presents at the Burke Medical Research Institute.

13. Mar 2016: Neuroscience Retreat at Ocean Grove.

Faculty roast, socks, and alpha-synuclein, and simple madness…

01. Feb 2016: Welcome, Katie! Kathryn Carnazza starts her rotation in the Burré lab.

17. Dec 2015: Departmental Holiday party at Hi-Life Restaurant & Lounge.

Food, drinks & fun.

04. Dec 2015: Jacqueline presents at the 65th Annual Meeting of the American Epilepsy Society in Philadelphia.

The committee was so excited about our work, that they selected our work not only for a poster presentation, but additionally for the Investigators’ Workshop poster session, highlighting the most outstanding abstracts on topics related to basic science and clinical research, and for a platform presentation talk.

24. Nov 2015: Thanksgiving potluck.

The 10th floor of the Belfer building celebrates.<

14. Oct 2015: John receives the 2015 Irene & Eric Simon Brain Research Foundation Fellowship at the 2015 Lunch & Learn Event in the Chrysler Building.

All five selected fellows present their summer research in presence of their mentors and foundation members:

· Dr. Bhatnagar & Jane Dobkin from Children’s Hospital of Philadelphia
· Dr. Burré & John Messinger from Weill Cornell Medical College
· Dr. Norris & Esther Putman from University of Kentucky
· Dr. Recio-Pinto & Jonathan Pun from NYUMC
· Dr. Serganov & Shivali Patel from NYUMC

01. Oct 2015: Jacqueline gives the Progress in Neuroscience Seminar.

21. Sept 2015: Welcome, Parinati! Parinati Kharel starts at Research Specialist.

14. Sept 2015: Welcome, Noah! Noah joins the Burré lab for his first rotation.

01. Sept 2015: Jacqueline receives a research grant from the American Parkinson Disease Association.

18. Aug 2015: Jacqueline talks at the Epilepsy Conference, Weill Cornell Medicine about “Synaptic dysfunction in infantile epileptic encephalopathies”.

27. Jul 2015: Welcome, André! André Pineda joins the Burré lab for a rotation.

30. Jun 2015: Jacqueline presents at the Parkinson’s Disease Gordon Research Conference. https://www.grc.org/programs.aspx?id=16890

26. Jun 2015: Jacquelines gives the BMRI seminar. “Synaptic dysfunction of Munc18-1 in infantile epileptic encephalopathies”.

07. Apr 2015: BMRI/Neuroscience Graduate Retreat in Ocean Grove.

Science plus other fun stuff.

01. Feb 2015: Jacqueline receives the Leon Levy Fellowship in Neuroscience.

01. Jan 2015: Jacqueline receives a grant from the American Epilepsy Society.

01. Sep 2014: Welcome, Zhao! Zhao joins the lab as postdoctoral fellow.

04. Aug 2014: Welcome, Jackie! Jackie Gottshall joins the lab as rotation student.

19. Jun 2014: Welcome, John! John Messinger joins the lab for a summer internship.

01. Feb 2014: The Burré lab is born 🙂